EXPLORING THCV - TETRAHYDROCANNABIVARIN
THCV is a homologue of THC. A homologue is a compound that belongs to a series of compounds, connected to each other. It can stand alone but must be a part of the chain to make the other compound, much like an ingredient in baking a cake. Flour can stand alone but you cannot have a cake without it.
In this analogy, you can think of THCV as the flour in the recipe to make the cake, which would be THC. THCV is a CB1 receptor antagonist. This means that it will bind to the receptor and activate the endocannabinoid system. It is a partial agonist of CB2 receptors. THCV is considered to be a stronger psychoactive compound than THC alone. That said, psychotropically speaking, the high created by THCV doesn’t last as long as the high created by Delta-9-THC or Delta-8-THC; it wears off much faster.
While THCV appears to have an inhibitive influence on some of the THC’s effects, it also enhances other things THC can do. This is not unique to THCV. Many cannabinoids work both with each other and against each other on several specific functions. This is known as the “entourage effect” and it is mainly considered to be beneficial, but research into the nitty gritty of cannabinoids, their various benefits, and how they interact with one another is still so new that we simply just don’t know the specifics yet.
“Levels of THCV in Cannabis Sativa from China, Nepal, Thailand, Afghanistan, and Pakistan have been reported as high as 53.7%.”
WHAT DOES THCV DO IN THE BODY?
Levels of THCV in Cannabis Sativa from China, Nepal, Thailand, Afghanistan, and Pakistan have been reported as high as 53.7%, which is pretty significant.
While Tetrahydrocannabivarin is considered more hallucinogenic than THC, the effects are thought to wear off much faster. However, more research is necessary for this to be a definitive fact rather than just a claim from some laboratories. One study so far has found that the increased heart rate, a typical response to THC, is inhibited by THCV. This might make THCV a better treatment for PTSD and anxiety for this reason.
While THCV appears to have an inhibitive influence on some of the THC’s effects, it also enhances other things THC can do. This is known as the “entourage effect”
Many don’t realize that THC tends to exacerbate paranoia and anxiety. THCV may be a much better treatment path for those with these and similar conditions. Of course, this is still speculation, but now that researchers have the ability to isolate and modify these compounds, more information is certain to materialize in the near future.
WHAT IS THE MEDICINAL VALUE OF THCV?
THCV seems to increase overall energy, helping mice and rats to burn more calories. By itself, it doesn’t appear to be a weightloss remedy but it may play an important role in helping people to be less sedentary.
In research studies for use in diabetes management, THCV has shown great promise in reducing insulin resistance and helping to maintain healthy blood sugar levels in the body.
THCV hasn’t been researched thoroughly enough. It has simply not had the attention or focus that THC or CBD have had. Only recently have some of the other potentially helpful cannabinoids, like Delta-9-THC and Delta-8-THC, been getting any focus.
Stay tuned for more information as research continues. The scientific community is pouring time and money into research, now that methods for isolation are improving and the public interest in these alternative medications, natural remedies, and the promise of cannabinoids is growing.