Perhaps one of the most promising cannabinoids at present, CBC is a member of the infamous “big six” cannabinoids. It is also currently being researched as a powerful cancer inhibitor. 


While there are over 100 known cannabinoids to date, the ‘Big Six’ cannabinoids refer to those cannabinoids that are both the most common, and have received the vast majority of research to date. They consist of:

  • THC
  • CBD
  • CBGA
  • THCA
  • CBDA
  •  CBC

CBC was discovered over fifty years ago, as an additional cannabinoid in the cannabis family of plants and is believed to hold great medical promise.  


Scientists believe that CBC works especially well when paired with other cannabinoids. This is specifically known as the Entourage Effect (E.E.).

While research into the details of the entourage effect in reference to specific cannabinoids is still in its infancy, Scientists are now able to separate the cannabinoids and single them out with molecular isolation technology. Future research will see scientists test cannabinoids in varying combinations, and at different percentages, to see which work best together and what amounts are optimal. 


CBC is converted from CBGA after it is heated. The dicarboxylic process happens when the plant matter is heated, smoked or vaped. It can happen in the industrial process of extraction if heat is specifically involved.

CBD is non-psychoactive. It doesn’t bind with the CB1 receptors in the brain. It does, however, bind with the CB2 receptors, as well as the vanilloid receptor 1 (TRPV1). It also binds to TRPA1, which is a ‘transient receptor’ which has been linked to the brain’s ability to perceive pain. When these receptors are activated, the body’s response is to release anandamide, which is one of our own naturally occurring endocannabinoids. 


CBC is also a neuroprotectant, like CBD. It shows very high potential in the field of Alzheimer’s research. In fact, neural stem progenitor cells are stimulated to replicate when introduced to CBC. This can help maintain brain function and recovery from inflammation, toxicity, and injury stress.


CBC is one of the cannabinoids that possibly could be the biggest game-changer for cancer treatment. The fact that it helps our own body to release anandamide and inhibit the uptake of it — the body uses it more slowly — means the anandamide stays in the system longer, helping with pain for more extended periods of time. We also know that CBC helps to fight the growth and spread of cancer cells in the body.

Mice were manipulated in labs to have cancerous growths. In these mice, CBC was found to show effectiveness in inhibiting inflammation and tumor growth, in regard to cancer cells. Anandamide has already been found to fight breast cancer. This means that the way CBC interacts to produce anandamide in the body could prove to be effective at treating breast cancer, and prevent the need for chemotherapy.

As those who work with cancer patients know, chemotherapy can drastically reduce the average patient’s ability to fight cancer on its own because of how draining the treatments can be. While chemotherapy is the best-known treatment, many also argue that it can be the very thing that kills many patients in the end.

CBC has also been shown to work exceptionally well for those who have osteoarthritis. It is considered to be more effective than traditional NSAIDs. When combined with THC, CBC can give tremendous relief to those in pain from arthritic knees and other joints.